MAL 49438

Isekai Yakkyoku

異世界薬局

Parallel World Pharmacy

SushiSuperLover

9.00 · 29 Sep 2025

Binged this anime due to the challenge on MAL, this is a 9/10 Anime. I'm usually the one saying Isekai is oversaturated and stuff which is..true. Then you get completely original titles like this as a reminder some shows do stand out despite not being headliner popular? Plain and simple, the MC combines his past Medical knowledge with the world's magical techniques. He is blessed by a healing god of sorts that gives him affinity of all magic types with a focus on Divine/Light. The dude lives to heal and I felt healed just watched him out of kindness and good will. Excellent incorporation of actual real life elements to create spells, supplies, materials, etc. To finalize, seeing him get healed with the warmness of a family confirms what Isekai is meant to be? A 2nd life done correctly

Asdfaeou

9.00 · 15 Mei 2025

What a wonderful, fulfilling anime. I felt it hit on so many notes, and went so many places, and you kinda got a taste of so many different things without feeling it lagged too long in any one place. MC: Pharma is a fine MC. He's smart, able and kind, without being sappy or overly confident. He realizes he has limitations, and always aims to do what is best, whilst thinking of others and their positions. He goes about trying to change the morals of the land around him while not shaming those who hold those morals. He is a very enjoyable MC who you are spurred to be interested in and root for. Surrounding Cast: You really do cheer for all protagonists in this anime. I can't stress that enough. There are even a few of which you don't read as protagonists upon introduction, but quickly come to change that view. Pharma is a child, and yet he isn't betrothed to some other child in some awkward "this is how the nobles do" plot that allows the jokes about marriage and sex and making babies that prominently feature in so many anime in this time of age/period piece setting. The characters around him are (for the most part) not annoying, you want them to succeed, and they understand Pharma has a mission and they're most fulfilled helping him get there. Plot: The plot along the twelve episodes really goes give you everything. To start you get the fun Isekai "Learn how MC is crazy powerful and the shocked reactions of those immediately around him as he makes everything instantly better" factor, but this show does NOT trip over the all too common trope of trying that for twelve episodes. The plot involves political intrigue, the inner-workings of a kingdom/civic matters, class system, religious struggle and the factors that go into dealing with how it feels when those of lesser power are right and you are wrong, even though you carried out your wrong ways in what was considered the highest of morale standings. Also, for it being a medicine based anime, it established that death IS inevitable very early on, and does not lean on the idea the "The MC can save everyone, in every situation, every time!" It's very maturely handled without being morose, simply real. Music/Animation: It's a beautiful, bright anime with lovely music. It's not the star of the show, but it doesn't hamper it either. I have no complaints in this department, just nothing really extraordinary to say either. Things I didn't like: Very few things. There is a "Beach" episode in which a character is told very simple instructions and basically just ignores it due to satiating a weeping child, and those scenes always annoy me because it's such an avoidable mistake made by someone who has proven many times they are capable of handing the situation, and illogical just choose not to in this moment. It also comes during what is basically the only filler episode (not completely filler, but a lot filler), it's really the only weak episode in the show. The MC and the major Sidekick also have an odd pairing in the first few episodes. For one, you don't really understand/aren't really explained WHY she is reacting somewhat negatively to his Isekai powers.... but then like a switch she completely changes her tune and that isn't well explained either. It felt like a very "This character needs to get from Point A to Point B, but we don't really know why, we just think it would be interesting if it happens" moment that shows do sometimes. I think they think it's character growth when it isn't. I want to make it clear everything I say in this section is nitpicky. It's a grand anime and there's no reason not to watch it. Please watch this anime. I feel it is unique in the Isekai realm, and worth the watch. There is so much more to this show than the premise granted, it remains an Isekai the entire show instead of it just being a jumping off point that is never really mentioned again, and I think you'll just have a great, satisfying time watching it.

hexashadow13

7.00 · 12 Jun 2024

tl;dr: An isekai that handles its pharmacy related aspects pretty well but is weak in most other areas. A highly skilled pharmaceutical researcher overworked himself to the point of death. He wakes up in another world in the body of a ten year old noble boy named Falma. And not just any noble but the son of the head of the de Médicis, a family of medical practitioners. Using his knowledge, position, and some special abilities called Divine Arts, Falma does his best to deal with the various medical issues he comes across and to advance health in general. This is very much an isekai where the protagonist is overpowered. Of course his scientific knowledge being significantly more advanced than anyone else is overpowered in and of itself. But he’s also overpowered in a much more traditional manner in that he has Divine Arts that seem to make him essentially invincible in combat. However, I felt that the narrative for the most part used these Divine Arts very effectively, in that they seem to take a back seat to his knowledge. Him having overpowered combat abilities means he doesn’t have to worry at all about putting himself in physical danger and thus the writing can just completely ignore anything related to that. His other Divine Arts also compliment his knowledge without superseding it. A lot of modern professions including doctors and pharmacists require the support of a large number of supporting roles. For example, medical diagnosis of many diseases would be significantly more difficult without complex tools made by bioengineers used to perform tests. And the development of drugs often requires a lot of heavy machinery designed by chemical engineers. As such, if the average modern doctor or pharmacist was transported into the past, they would be incredibly limited in what they could accomplish. Falma has the ability to magically see if others have a medical condition, and though he can’t magically figure out what the condition is, the magic does tell him if he determined the right one. Furthermore, he can magically generate any chemical he knows the composition of. This essentially replaces what he would have access to in a modern setting and allows the anime to focus on showing him dealing with diseases and such. This allows for pretty decent story telling, while also imparting a lot of actual information on drugs and medical best practices on the viewer. Unfortunately, as the anime progresses the narrative starts deviating from that. The final arc heavily involves Falma dealing with issues directly through his Divine Arts. This feels kind of cheap and contrary to what the focus of the anime was earlier. There’s also a much larger emphasis on just regular old combat between characters using their Divine Arts. But Divine Arts in general aren’t really fleshed out at all so them actually being in the focus like that also feels really random and not that interesting. The final arc also seemed to throw in a cartoon villain for some reason even though it was completely unnecessary. As a result, even though I found the topic of the final arc, epidemics, really interesting, I found the arc overall incredibly underwhelming and my final impression of the anime was pretty weak. I also found it kind of strange how the anime implemented the isekai aspect. The protagonist wakes up as ten year old Falma, but it doesn’t make clear at all how. Did the original Falma die and the protagonist essentially replaced him? Did he hijack Falma’s body and the original Falma is still somewhere in there? Is Falma his reincarnation, and he just regained the memories of his past life? Or is it something else entirely? It’s not like this aspect isn’t dealt with at all. Rather, in the beginning there are a bunch of details that it feels like are foreshadowing something or other. However, they go nowhere and no solution is provided. I feel that this resulted in Falma overall being fleshed out far less than he needed to be which resulted in him being a pretty flat character. The rest of the cast were pretty lackluster as well. There are a lot of somewhat interesting and somewhat likable characters. But no one is developed enough to get all that invested in. The art and animation are okay but not particularly great. Design wise, it was actually pretty good early on. However, it got more and more dull as it went on. I think Eléonore is a great illustration of this, in that early on she seemed to get new outfits constantly and most all were pretty good. But as things progressed she got fewer and the ones she did weren’t as nice. I suppose the designs did become more realistic and practical, but that doesn’t change that they’re more boring. The OP and ED are decent enough in terms of the song and visuals. The soundtrack is decent enough but not particularly memorable.

mushimk

6.00 · 20 Mar 2024

Any cure is a slow process. Unlike this anime, for that matter. Rushed towards the last few episodes, which crush every bit of expectations you were slowly accumulating over the progress of an anime with an unusual theme. It's an absolute pity, because for those who enjoy a nice change of pace, this anime was starting good, if not - at the very least - steadily. Then suddenly, it comes down crashing when every medical problem is being solved by godly powers which absolutely undeserve the anime theme. If you've nothing better to do, you can watch this anime but keep in mind you're likely to be disapointed.

CTW15

3.00 · 1 Mar 2024

Ive never written a review, but these characters pissed me off to the point where I needed to vent. The show started off fine. The scientific focus of the first episodes is quite fun and its nicely pased. However, after a couple of episodes, this show becomes unbearable due to these characters. Every single prominent characters is obsessed with the MC. The constant cries of admiration and moments where other characters are in awe of the MC get old after about 12 seconds. There is 0 depth to any of these characters, 0 character development and the story is too stale to make up for any of it. Ive seen some Isekai trash in my time, but at least most shows have some redeeming quality, or are bad to the point where it gets funny. This is neither, it just pissed me off. Why they felt the need to make the most abnoxious 8 year old girl and a 24/7 awestruck adult mage 2 of the main characters is beyond me. The MC is not as bad, hes just incredibly bland, like almost ubelieveably bland. I somewhat enjoyed the first couple of episodes, but what follows is so abnoxious that I cannot score this more than a 3.

sukinana

6.00 · 18 Jul 2023

As someone who is an Isekai junkie, I am all in for Isekai shows that try out new concepts because the Isekai genre is broad and stuff you can do with it is amazing if you're creative enough. Now I thought this show was one of those happy go luck shows where nothing insanely bad happens(well it is) but there is a dark side to this show as well (they haven't really gotten super dark yet, will probably not happen lol) I liked how patients aren't treated with nonsensical OP abilities that the MC has and its actually proper treatment that you'd get from a doctor or surgeon in our world, Not to say that it isn't the case but there are limits to what he can do with his abilities although they are stupidly OP but thats just Isekai logic. The plot is just what you'd expect from an Isekai show, MC was a medical researcher in his past life and he dies due to overworking himself and he reincarnated in a different world. One of the things that I actually liked is how they gave us introduction about the MC unlike most Isekai shows where MC suddenly just gets hit by a truck and things start off there with little to no effort of introducing us what type of person the MC is nor showing his background. I was really enjoying this show, Until I wasn't.. the story just fell off halfway through the show, It had a lot of good moments like the moment with the Father pharmacist who had a sick daughter, That was very touching and my favorite thing about the show. There is also the way they dealt with the sudden economic boost with new medical knowledge being shared by the MC to the public like women cosmetics, medications, and ways to deal with cancer that wasn't curable until the MC made medications for it and because its in a medieval setting so yes. The animation was quite nice though not to say that it's amazing, The few fight scenes that happened we're pretty okay I'd say animation is around the average level. For the character's I don't really have that much to say about them since I didn't find anyone remotely interesting all of them we're pretty bland but I guess the MC acts like how a medical expert would so I guess I like that. Overall I really really.. REALLY want to love this show more but the second half just ruined it for me, Hoping that things get better at Season 2 if it ever gets one. TL;DR: An OKAY show to watch if you have nothing else in your watchlist or if you just love Isekai and is interested in the premise of this show I'd say its worth a chance.

ChaosGiantMemes

6.00 · 1 Feb 2023

I do have some personal bias towards this isekai anime as I've been waiting for a show that delves into modern medicine, however this anime left so many things out while having many good opportunities wasted. This whole show had a good premise but somehow the author wasted it's potential. After binge watching this show, it was a slow climb as the main character had to overcome certain challenges but once the showed peaked things went downhill and fast. Certain areas of the show that could've had more time spent were completely rushed out the door in order to just keep moving the plot along to fit the 12 episode quota and the show suffers for it. Of course you have your standard "OP isekai character" guy but he's not there to fight demon lords, he's just there to make medicine and make people feel better. Yet frankly him having OP magic felt more like a plot convenience because the writer was lazy or all his medical information came from a 10 minute Google search, having the main character have OP magic was very unnecessary and the writer could've left it at "He was born with the rare ability to use creation magic". Not "Oh BTW he has enough Magic power to shoot water that can obliterate a kingdom". The cast of characters is either passable or interesting enough with 3 of the most interesting characters is the main character himself, his new biological father and the Queen herself (No not the Queen of England). The music that plays in the show is good enough to set the right tones in every scene but they're nothing to take notice of. The animation quality is average with no CGI being used during action sequences. The show has it's high points when tensions become high but is immediately overshadowed when the show decides to progress too quickly to allow the watcher to accept new information or when the writer gets lazy and decides to put in key information in exposition. When the show does decide to delve into the modern medicine aspect, you're not going to get Doctor Stone levels of detailed explanation, you'll just have the same amount of information as you would get in a 10 minute google/wiki search. Overall the show itself is an OK watch, it's worth it to watch at least once if you have nothing else to watch but this particular isekai itself is nothing special. If you're interested in the premise of this isekai, go and give it a watch, otherwise you can keep this in the back shelves of your watch list.

Ekamin2002

8.00 · 15 Des 2022

An isekai that is actually decent. Going into this I expected it to be some random dude transported into a fantasy world and stay a chill life on a county side while selling some magical healing potions or something using some god given alchemy skill. But I was wrong. The Mc actually had a medical background and uses that knowledge to treat people with actual medicine. Comparatively the premises could be said to be similar to Assassin Isekai (The World's Finest Assassin Gets Reincarnated in Another World as an Aristocrat) but of course Medicine instead of killing. I personally love it when the world have a clear magic system. (yes, I'm calling you out Harry Potter) There is no leveling up or progress. But, there are a clear set of rules for it's magic, like a regular person only being able to cast with a wand, people born with magic are nobility and can only use given attribute or something out of the ordinary is seen as heresy or god's blessing, like the dark ages. There is only limited healing magic so they has to rely on the advancements of meds. It's like visiting the 13 hundred's inturms of medicine while implementing the scientific miracles of modern medicine. Of course the MC is OP and blessed by the gods but it's not something that gets in the way. Also the ending is ok at best, I would've enjoyed it if it continued but it's fine. It has medicine, magic, politics, social economics. So if you like isekai but want something decent, go for it. Also the start of the ending theme reminds of House theme song.

NerdistRay

7.00 · 17 Nov 2022

This is a wholesome anime where everyone is smiling around with an MC who is overly kind and laughs awkwardly every time someone praises him. And since it's a pharmacy setting, everyone goes all like "woah, amazing, unbelievable" every time MC does basically anything since this world has ancient medical knowledge. And there's a 9 year-old female maid who acts all kawaii with a pink flowery hearty background, you know what I'm talking about. Things usually always go the fairy tale way with everyone happy. So if you're the kind of person who finds this annoying or just dislikes it in general, you might not like this anime. But things you might like in this anime is the relatable and easy-going MC, lovely parents and adorable younger sister, supportive characters with actual role who aren't just eye-candy and actually reasonable people who act like they do have some brain instead of some animes where characters act all stupid and basically serve as a stepping stone for MC. I especially sympathize with MC's past and his motivation for pharmacy, it actually managed to make me a little sad. MC also has very OP abilities but instead of being cliche, it feels pretty fresh.

animelover12307

9.00 · 27 Okt 2022

i know for most people that this is not what an isekai anime they are looking for, but this is the kind of anime i wanna watch since it's simple but good, and the voice actor of falma is really good as well, it fits the voice and the character as well, i don't know how i can really explain this anime here but i will say for now this is the best isekai anime 2022 i've watched :D (i really hope they would at least continue the light novel and manga until the end if there is no another season of this anime cuz it's really interesting to see what would happen in the future)

uniDJar

8.00 · 18 Okt 2022

A nice Isekai snack to binge on. For me who was starving for a good isekai, this one was like a god-sent. It had that perfect balance of fantasy-medical-OP MC characteristics, that made me binge it in a single sitting. All the characters are likable and the story is intriguing ,yet not hard to digest and provides a soothing sensation after watching. I especially liked the fact that MC didn't go on a harem building overdrive as seen in other isekai works. They kept it simple and beautiful, with good animations. You will definitely enjoy this one. A good choice for a rewatch.

Akusins

10.00 · 29 Jun 2025

Loved it. It’s not every day you see an anime that puts some focus on epidemiology and microbiology. It was nothing short of very welcome fan service to those of us with research backgrounds and expertise in those fields who also love anime. I wish they could have been a little more technical with everything, but overall it was very fun. Haven’t binge-watched an anime in a single day in a while. I’m not much of a critic of media and don’t really have much knowledge of plot devices and the different elements of storytelling, so I’ll just say some things I think might be relevant. I like how the humbleness of the MC is kept to a minimum. I like how the MC isn’t clueless about his advantages and doesn’t think he’s super weak. I love how the show also dipped its toes into public health and stayed true to the motto “prevention is better than cure.” When dealing with disease and illness, preventing a disease that could possibly take your life is better than fighting the disease and hoping the medicine controls the pathogen enough. I’m an easy guy to please when it comes to entertainment. I don’t have many gripes, other than I wish they could have been a lot more technical about things—like explaining in depth how bacteria staining works, why staining bacteria can be essential when determining the best antibiotics to use, and stuff like that.

maoginko

8.00 · 31 Des 2024

Parallel World Pharmacy is one of the best isekai i've seen in recent years. Good animation, good soundtrack, well written characters, an intriguing premise, and solid world building can all be found in this gem of a show. The story centers around a pharmacist who passes away in his sleep from overworking at his lab. He then reincarnates into the body of a 10 year old boy named Farma from a long noble lineage of outstanding pharmacists and gains the blessing of a god to practice medicine all he likes in this new magic and science filled world of his. It's quite interesting to see his adventures in introducing this new world to modern medicine and truly developing the level of patient care he longed for in his past life. It was a joy to watch he and his companions grow and shape the medical field and i would love a season 2!

SoulThiefRei

8.00 · 4 Agu 2024

If you’re tired of most Isekai filled with fan service and overpowered MC’s then watch this. It takes Isekai into a slice of life following a pharmaceutical worker who gets reincarnated into a less advanced world and runs his own pharmacy. It has everything, amazing scenery, good sub and dub, a great power system, and amazing characters. I definitely would recommend. The only downside is the fact it has 1 season. It really opened my eyes to just how vast and diverse animes of the same genre can be. I’m used to watching Isekai like That time I got reincarnated as a slime, eminence in shadow and things like that with broken characters, fan service, and unrealistic world. This had none of that, it was as if i was watching a show on someone’s average life and them making the world a better place. Instead of trying to fit in this anime stands out which I think makes it that much more special and enjoyable.

TasRook

7.00 · 22 Feb 2024

Pretty good. A middle aged, very smart pharmaceutist and a research lab worker gets sent to a medieval fantasy world where he replaces the son of an archduke, who is also a brilliant medicine man. On top of it he gets OP magical powers. And yeah, his name is Farma Medicis. Very clever... There is quite a bit of drama in the first few episodes about his new found powers and knowledge and I really liked the realistic attitude of the people around him. Especially the father. The man is really likeable. Which will be a common theme as there is really only one bad person in the whole show and he appears only at the end. Which is my biggest gripe with it. It's just too perfect. People are nice, polite, friendly and even those that aren't outwardly so, are still good on the inside. Early into the anime the MC befriends the head of the country, because obviously, which also gives him OP political and financial powers, which makes him pretty much socially untouchable and he becomes the go-to person with anything sickness related. (I'm sick so I found all the interactions between them super enticing as I was imagining this powerful woman to be an unredeemable cougar towards our shota protagonist.) Also cosmetically related. Because again, obviously, we can't have an isekai without a Japanese person getting rich off selling shampoo. Anyway. There is also some touching and well written parts, like the father-daughter plot line which made me shed a tear, some drama related to religion, and at the end we get a big bad guy causing chaos. The last part was really disappointing. The stakes suddenly became way too big as until now we've been treating only common ailments, if barely any at all, and now the whole world is about to crumble and our protagonist is at the centre of it. I guess the creators wanted a big dramatic sendoff, but it doesn't fit in at all. It all felt rushed, ridiculous and bored me out of my mind to the point I was skipping though parts. So yeah. Pretty good. 6.5/10. Don't expect too much.

AriaHime

9.00 · 11 Jan 2023

Ok so here’s the thing, i’m someone who’s busy with real life stuff and to save time I only watch animes that has ratings 7.8 and above… and honestly if i did not chance upon this gem on Musa Asia Youtube and have seen the nice comments there i would have never know of this show. Anywayyyy the anime has nice animation, Voice acting, and has a decent OST. Great story progression as well. Isekai is not the newest thing and the pace helped to maintain interest. There is also a good balance of science, economics, and morality ~> encompassing “Pharmacy” as a discipline and its kinda cool in its own way. I think i enjoy it more than other isekais, coz there is a structure, and it stayed true to that structure which is Pharmacy. Unlike other isekais that are kinda all around the place. This one is consistent and coherent. Over all vibe, very calming, might not make you LOL, but definitely can make you smile kind of show… very heartwarming too ^^ Okay a bit of rant mehehe I don’t get why ppl always complain abt charas being Op in isekais tho.. I don’t get why they expect isekai charas to like be a pleb in the new world too, like..i mean what’s the point of being reborn if you’re a pleb on both worlds? If it’s me Might as well just let me rest in peace alright?! Soo ya see, the OPness of the main chara is something i can live with. some MaL revs are getting ridiculous nowadays.. or meh prolly just me and my aunty vibes that’s not in tuned with the popular taste these days and iccl End of rant Mehehe Enjoy watching anime!

MyDogTige

7.00 · 12 Okt 2022

This had so much promise. After the first two episodes I was really hooked. It carried on in a similar manner and was not terrible but by the time it reached episode 8 or so, it really lost its spark. It was incredibly redundant. The real world representation of epidemics and the way we handle them was actually very accurate from what I'm aware of. All things like hazmat suits and masks were present, something that we became accustomed to in the covid-19 pandemic. Unfortunately, almost all growth for the show halted late in that season. I think what was most disappointing was the end. Bad stuff shows up out of nowhere, but is neutralized and destroyed almost instantly and then the show is done. It really left me feeling empty and incomplete.

aurora_aeterna

5.00 · 7 Okt 2022

tl;dr gets worse as the show goes on but still worth the watch. Another isekai for isekai summer, at least Isekai Yakkyoku tries to be a different sort of isekai by isekai'ing its MC into a pre-Victorian-era isekai as an isekai doctor/pharmacist instead of some kind of isekai combatant. Too many isekai's for you in that sentence? Welcome to how I feel about this summer. For all the people saying this is a unique idea: it's not. I'll give points for this being the first, considering it started serialization first, but it does come after the other two anime. Points for being the best one so far though since both Cheat Kusushi and Yuusha Party were subpar to put it lightly. Where the other two failed Isekai Yakkyoku succeeded, for the most part. It has a good exposition, a plot that doesn't feel too forced, and characters that are at least likeable. I don't want to go too far in praising the show. It's not some kind of genre-defining anime and it definitely has its faults. Top issue with it is all the characters are flat. His sidekicks could've been copypasted from any other anime and it wouldn't have made a difference. There's not really any change beyond initially doubting MC Farma before he brings them to his side with his sick pharma raps. And on the topic of his pharma knowledge I appreciate the effort that went into the research of actual drugs but just naming them doesn't help at all. Cue that overquoted Clarke quote about any sufficiently advanced technology. Lastly in the interest of not spoiling anything I'll just say that as the story goes on some of the resolutions lack the depth that I was expecting from the tone that the first episode or so set. Isekai Yakkyoku could've really been great, with a little tuning of the content and characters but lacking that at least it's still average. Worth a watch if you're sick of hack-and-slash isekais.

EliteEmperor

5.00 · 7 Okt 2022

Decent isekai series, it could have been better but it was really something else. The knowledge of the Mc and the comparison to our real world is superb. The art style and the animation are also good. The story is decent, the characters didn't much develop this season, the Mc had good abilities when considered he is a pharmacist and the magic shown in the episodes is decent magic. I particularly liked the Mc and his abilities. The story was mid for me. I have mixed feelings about recommending this. The story felt a lot blank. It could have an adventurous storyline could have made it interesting or if they have improved the villain in this story and made him even stronger it could have been a lot more interesting. This is strictly my opinion. I give it 5/10

JustKeepBinging

9.00 · 2 Okt 2022

This was a really cute anime and very wholesome. The mc knows the dangers of exposing himself but he is so OP and humble at the same time. There was literally half the anime about one event but everything connected really well. You can see the character development and how much he grows, and he is literally trusted by everyone he meets. I questioned whether the anime was still about medicine, but the cause and everything they were doing was also related to medicine. Its amazing that such a large scale conflict was based on medicine and could create such a great storyline.

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